Centre for Arab Genomic Studies (CAGS) reports Arabs suffer from one of the highest rates of genetic diseases in the world. Some 906 genetic disorders have been identified in Arabs and their descendants, with several diseases having an incidence of more than 100 cases per 100,000. These include thalassemia (a blood disorder), diabetes, breast cancer and Down's syndrome. Some of the disorders have reached epic proportions like sickle cell disorder, heart diseases, alpha-thalassemia, and diabetes mellitus. Some of the main genetic diseases prevalent in the Arab countries are hemoglobin disorders, birth defects, inherited metabolic diseases and neurogenetic disorders.
Over 70% of Arab genetic disorders are Autosomal-recessive, meaning the defective gene has to be found in both father and mother, and since the gene pool are similar in population (males and females alike since autosomal chromosomes are admixture from father and mother, in closed societies (marriages from same sect endogamy, or same tribe or even from same country, or even from same block of countries since gene pool is similar in Geographical blocks.
Our Middle-Eastern community kit is designed to assess your risk for diseases prevalent in the community, which includes Cystic Fibrosis, Alpha/Beta Thalassemia, Familial Mediterranean Fever (FMF), Atypical hemolytic uremic syndrome, Spondyloarthropathy, Autosomal recessive polycystic kidney disease, Anencephaly, Hirschsprung disease, Type 2C of limb-girdle muscular dystrophy, Laurence-Moon Syndrome, Faciodigitogenital syndrome, Hypophsphataemic rickets and hypercalcuria, Canavan’s disease, Usher syndrome type 1 and Stuve-Wiedemann. Moreover, our kits are also designed to assess the genetic risk of diabetes.